When admitting a client with mononucleosis, which isolation precaution should the nurse initiate?

When admitting a client with mononucleosis, initiating droplet precautions is essential because the virus responsible for mononucleosis, often Epstein-Barr virus, can be transmitted through respiratory droplets when the infected person coughs or sneezes. Droplet precautions involve wearing a mask when within close proximity (typically within 6 feet) of the patient, as well as ensuring proper hand hygiene and using appropriate protective equipment when interacting with respiratory secretions.

Standard precautions are universally applied but do not specifically address the transmission concerns associated with droplets. Airborne precautions are reserved for pathogens that can remain suspended in the air for extended periods and can be inhaled, such as tuberculosis. Contact precautions focus on preventing transmission through direct or indirect contact with the patient or their environment, which is not the primary concern with mononucleosis. Thus, implementing droplet precautions is the most effective means to prevent the spread of the infection in a healthcare setting.