When should pancrelipase be taken by an adolescent with cystic fibrosis?

Pancrelipase is a medication that contains enzymes aiding in the digestion of fats, carbohydrates, and proteins. For an adolescent with cystic fibrosis, it is most effective when taken with meals. This timing ensures that the enzymes are present in the digestive system when food is consumed, which helps in the breakdown and absorption of nutrients, an essential consideration for managing the nutritional needs of someone with cystic fibrosis.

Taking pancrelipase with meals aligns with the body's natural digestive process, thus maximizing the effectiveness of the enzyme replacement. This is crucial for individuals with cystic fibrosis, as they typically have pancreatic insufficiency and may struggle to digest food adequately, leading to malnutrition and related complications. In contrast, taking the medication before or after meals wouldn't provide the necessary digestive enzymes during the critical time when food is being processed in the stomach and intestines.