Which medication should a nurse administer for a client experiencing postpartum hemorrhage?

For a client experiencing postpartum hemorrhage, administering Methylergonovine is appropriate because it is a potent uterine stimulant that promotes uterine contractions. These contractions help to control bleeding by compressing the blood vessels that were disrupted during delivery. Methylergonovine is specifically indicated for the management of postpartum hemorrhage caused by uterine atony, which is when the uterus does not contract effectively after childbirth.

In contrast, Oxytocin, while also a uterotonic used to manage postpartum hemorrhage, is not the best choice for all situations, especially in cases where Methylergonovine may be more effective or necessary due to the severity of the hemorrhage. Hydrocodone is an opioid pain medication not indicated for postpartum hemorrhage management, as it does not address the underlying issue of uterine atony. Hydrocortisone is a corticosteroid used to manage inflammatory conditions and has no direct effect on uterine contraction or bleeding in the postpartum period. Thus, Methylergonovine serves as the most targeted and effective medication option for addressing this specific clinical situation.